The presentation will give an overview of analytical strategy for BMS-986483 (LNP) drug product, with a focused discussion on 1) encapsulation efficiency determination of the siRNA ; 2) surface exposed targeting agent analysis.
Learning Objectives:
Understanding the methodologies and considerations involved in determining encapsulation efficiency of siRNA within lipid nanoparticles.
Gaining insights into the novel analytical techniques used to analyze surface-exposed targeting agents on lipid nanoparticles.
Exploring potential challenges and solutions associated with the analytical characterization of SiRNA LNP formulations.
